COVID 19: Latest Update: Vaccination Effectiveness and Risk Jan 2022

COVID 19 Knowledge and Simulation Platform

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Vaccine Effectiveness

Washington State Dept. of Public Health Dec 29,2021

 

Death

 

Hospitalization

 

Infection (Case Rate)

mRNA Vaccine Graphic – What happens after injection.

 

Vaccine Risk

Adverse Events After mRna Vaccination Jama Sept 2021

  • Day 1 – 21 vs. Day 22 – 42 after injection
  • 6.2 million patients
  • No difference in the following
    • Stroke
    • Appendicitis
    • Myocardial Infection
    • Venous Thromboembolism
    • Bell’s Palsy

Myocarditis

Literature Review 

Clinical Studies 

  • NEJM Aug 2021      Myocarditis risk slightly higher than control group but 5x lower than COVID 19 Infection group
    • 884,828 vaccine group
      • Myocarditis vaccine 2.4/100K 3x control  
      • Median age 25,  90% male
    • COVID 19 infection group
      • Myocarditis 11/100K
      • Arrhythmia  166/100K
      • Acute Kidney Injury  62/100K
      • DVT       43/100K
      • MI          25/100K

 

  • NEJM Dec 2021      “As acknowledged by the authors, temporal association does not imply causation, and the risk of vaccinal myocarditis is very low.”
    • 2.5 million subjects
      • Myocarditis risk 2.1/100K  median age 25  90% male
        • 76% mild
        • 22% intermediate
        • No deaths
        • All who were available to f/u returned to normal

Pericarditis

  • JAMA Aug 2021
    • 2 million vaccinations
      • 1.8/100K  median age 59  85% male
      • No deaths
      • All recovered

Anaphylaxis

  • CDC data base
    • 0.3/100,000

Death

  • CDC Data Base    No increased risk vs control
    • “There is no increased risk for mortality among COVID-19 vaccine recipients.”

Mayo Clinic Addresses Vaccine Risk

 

 

CDC VAERS Reporting System

  • Who reports
    • Healthcare providers
    • Vaccine manufacturers
    • The public 
  • Interpretation
    • VAERS data are derived from a passive surveillance system and represent unverified reports of health events, both minor and serious, that occur after vaccination.
    • While some events reported to VAERS are truly caused by vaccines, others may be related to an underlying disease or condition, to drugs being taken concurrently, or may occur by chance shortly after a vaccine was administered.
    • In some media reports and on some web sites on the Internet, VAERS reports are presented as verified cases of vaccine deaths and injuries. Statements such as these misrepresent the nature of the VAERS surveillance system.